In this publication, we provide a comprehensive update of the situation with GMOs in SA. Since our last South African update on genetically modified crops, and the transnational companies that control the technology published in 2008, GMOs have become even more entrenched in the country’s agricultural landscape. Over three quarters of South Africa’s maize is now GM, Roundup Ready soybean cultivation has increased nearly fourfold. If Pioneer Hi-Bred’s acquisition of Pannar seed is accepted, we are about to relinquish all control over our seed system to two US multinational corporations. During 2010 and 2011, nearly 6 million tons of GM maize was exported to destinations in Africa and Mexico, the centre of origin of maize.